I have been running for several years now, in that time i have run alone, ran with friends in groups and one to one and ran with strangers.
what i have found is in the first instance the importance of mental health and wellbeing through exercise. I always feel much better after a run than before.
secondly (usually when more one-to-one running ) the amount you vent or talk through things on your mind more openly, this is what i would like to focus on more as it really helps clear the mind.